Corpus callosum index and long-term disability in multiple sclerosis patients
نویسندگان
چکیده
منابع مشابه
Optical Coherence Tomography and Corpus Callosum Index in Cognitive Assessment of Multiple Sclerosis Patients
Background: Multiple Sclerosis (MS) is a neurodegenerative disease of central nervous system. Different approaches have been developed to study MS progression and cognitive dysfunction as the major symptom of the disease. The current study compared Optical Coherence Tomography (OCT) and Corpus Callosum Index (CCI) for the early evaluation of cognitive dysfunction in MS patients. Objectives: T...
متن کاملCorpus callosum in multiple sclerosis.
A neuropathological study of 20 multiple sclerosis brains using celloidin-embedded slices was carried out to assess the extent of changes in the corpus callosum. Severe atrophy of the callosum was found in cases with marked hydrocephalus. Demyelination of the callosum varied in extent from slight involvement (with a few small plaques) to almost total myelin loss. A clinical history of mental de...
متن کاملCorpus Callosum deformation analysis in Multiple Sclerosis
Dans cet article, nous présentons une méthode de mesure des déformations volumiques du Corps Calleux (CC) consécutives à la Sclérose En Plaques (SEP). Une méthode de segmentation 3 D du volume d'intérêt basée sur les modèles déformables est proposée. Des mesures sont ensuite réalisées sur ce volume à partir d'Imagerie par Résonance Magnétique (IRM) cérébrales. La variabilité de la forme géométr...
متن کاملInfluence of Corpus Callosum Damage on Cognition and Physical Disability in Multiple Sclerosis: A Multimodal Study
BACKGROUND Corpus callosum (CC) is a common target for multiple sclerosis (MS) pathology. We investigated the influence of CC damage on physical disability and cognitive dysfunction using a multimodal approach. METHODS Twenty-one relapsing-remitting MS patients and 13 healthy controls underwent structural MRI and diffusion tensor of the CC (fractional anisotropy; mean diffusivity, MD; radial ...
متن کاملImpairment, disability and fatigue in multiple sclerosis
Background: Identifying the predictors of pain is important for both health professionals and researchers, because pain has repeatedly been found to be a strong predictor of activity limitations and participation restrictions. The objective of this study was to determine the predictors of pain presence and severity in a large, well-designed sample of community dwelling individuals with multip...
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ژورنال
عنوان ژورنال: Journal of Neurology
سال: 2010
ISSN: 0340-5354,1432-1459
DOI: 10.1007/s00415-010-5503-x